Upper airway inflammatory diseases and bronchial hyperresponsiveness
نویسندگان
چکیده
منابع مشابه
Bronchial hyperresponsiveness and airway inflammatory markers in nonasthmatics with allergic rhinitis.
Bronchial hyperresponsiveness (BHR) is a characteristic feature of asthma which is often associated with airways inflammation. However, some patients with allergic rhinitis and no clinical evidence of asthma also exhibit BHR. This study therefore investigated whether inflammatory cell infiltrate is present in the induced sputum of nonasthmatic subjects with allergic rhinitis during the pollen s...
متن کاملLung parenchymal shear modulus, airway wall remodeling, and bronchial hyperresponsiveness.
When airways narrow, either through the action of smooth muscle shortening or during forced expiration, the lung parenchyma is locally distorted and provides an increased peribronchial stress that resists the narrowing. Although this interdependence has been well studied, the quantitative significance of airway remodeling to interdependence has not been elucidated. We have used an improved comp...
متن کاملAirway inflammation, basement membrane thickening and bronchial hyperresponsiveness in asthma.
BACKGROUND There are few data in asthma relating airway physiology, inflammation and remodelling and the relative effects of inhaled corticosteroid (ICS) treatment on these parameters. A study of the relationships between spirometric indices, airway inflammation, airway remodelling, and bronchial hyperreactivity (BHR) before and after treatment with high dose inhaled fluticasone propionate (FP ...
متن کاملSmall Airway Impairment and Bronchial Hyperresponsiveness in Asthma Onset
PURPOSE Our study tried to find a relationship between baseline FEF25-75% and airway hyperresponsiveness (AHR) and whether a greater FEF25-75% impairment may be a marker of a more severe hyperresponsiveness in subjects with normal FEV1 and FEV1/FVC and suggestive asthma symptoms. Besides, we tried to asses a FEF25-75% cut-off value to identify hyper-reactive subjects. METHODS 4,172 subjects (...
متن کاملClinical and inflammatory determinants of bronchial hyperresponsiveness in COPD.
Bronchial hyperresponsiveness (BHR) is regarded as a hallmark of asthma, yet it is also present in a considerable number of chronic obstructive pulmonary disease (COPD) patients. Epidemiological studies have shown that BHR provides complementary information to forced expiratory volume in 1 s (FEV(1)) for development and progression of COPD. We hypothesised that the severity of BHR and its longi...
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ژورنال
عنوان ژورنال: Journal of Allergy and Clinical Immunology
سال: 1988
ISSN: 0091-6749
DOI: 10.1016/0091-6749(88)90176-5